Reverend Solomon Stoddard, one of New England's most esteemed religious leaders, in "1703 formally proposed to the Massachusetts Governor that the colonists be given the financial wherewithal to purchase and train large packs of dogs 'to hunt Indians as they do bears'."

Massacre of Sand Creek, Colorado 11/29/1864. Colonel John Chivington, a former Methodist minister and still elder in the church ("I long to be wading in gore") had a Cheyenne village of about 600, mostly women and children, gunned down despite the chiefs' waving with a white flag: 400-500 killed.
From an eye-witness account: "There were some thirty or forty squaws collected in a hole for protection; they sent out a little girl about six years old with a white flag on a stick; she had not proceeded but a few steps when she was shot and killed. All the squaws in that hole were afterwards killed ..."
More gory details.

By the 1860s, "in Hawai'i the Reverend Rufus Anderson surveyed the carnage that by then had reduced those islands' native population by 90 percent or more, and he declined to see it as tragedy; the expected total die-off of the Hawaiian population was only natural, this missionary said, somewhat equivalent to 'the amputation of diseased members of the body'."